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Granulocytic sarcoma is an uncommon tumor composed of granulocytic precursor cells. Myeloid sarcoma (also known as granulocytic sarcoma, chloroma, and extramedullary myeloid tumor) is defined as an extramedullary mass-forming lesion of immature myeloid cells (Fig. Granulocytic sarcoma of the gastrointestinal tract most frequently involves the small intestine and most often presents with abdominal pain and obstruction. Intracardiac echocardiography-guided biopsy of the tumour revealed the tissue diagnosis-granulocytic sarcoma of the heart. As predicted by the unusual clinical manifestations and radiological findings, the patient's survival was short. 14.20) and is diagnostic of AML, even without 20% blood or marrow blasts. Histological diagnosis can be difficult in patients with poorly differentiated orbital tumours and no evidence of systemic leukaemia. Cardiac magnetic resonance imaging and computed tomography demonstrated extracardiac tumour invasion of the free atrial wall extending to the right pulmonary hilus. Brain MRI showed 2 well-circumscribed right parietal lobe lesions (one lesion shown above). View large Download PPT. Spahr J, Behm FG, Schneider V. Granulocytic sarcoma is an unusual form of tumefaction caused by acute granulocytic leukemia. Pan T cell marker Diagnosis of myeloid (granulocytic) sarcoma (J Clin Pathol 2005;58:211) Classify subtypes of T cell lymphomas and low grade B cell lymphomas Differentiate pulmonary MALT lymphoma (CD20+ CD43+) from lymphoid hyperplasia (CD43 negative, Am J Surg Pathol 2002;26:76) Preleukemic granulocytic sarcoma of cervix and vagina: initial manifestation by cytology. On rare occasions, the lesion precedes the leukemic phase and presents as a mass with a normal peripheral white cell count. Be- cause it occurs in a variety of clinical settings and because the tumor cells are primitive it is frequently unrecognized during life. A 56-year-old man had a history of acute promyelocytic leukemia and had been in remission for 2 years. This is the first report to document a granulocytic sarcoma in the cerebellum as the primary presentation in a patient with APL and abnormal coagulation. This presentation details the authors’ experience with 61 biopsy-proven granulocytic sarcomas. Spinal fluid cytology was negative for malignant cells. A case of CD56+ cutaneous aleukaemic granulocytic sarcoma with myelodysplastic syndrome. Granulocytic (myeloid) sarcoma (GS) is a rare hematological neoplasm composed of immature myeloid cells at an extramedullary site which may precede leukemia; nevertheless, the most frequent clinical presentation is secondary to acute or chronic myeloid leukemia, or myelodysplastic syndrome [1, 2] developing within an average of 6–12 months after primary diagnosis []. Eleven patients, 13 to 76 (mean, 40) years of age, had granulocytic sarcoma of the female genital tract (FGT) (ovary, seven cases; vagina, three cases; cervix, one case).In nine cases, the FGT involvement was the initial clinical presentation of the disease, and in the other two cases, the FGT involvement was discovered during a relapse of acute myeloid leukemia. AIM Orbital granulocytic sarcoma is a localised tumour composed of cells of myeloid origin. granulocytic sarcoma. He developed the new onset of seizures. 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